Localised Evidence and Decision-making (LEAD)

Addressing the need for locally-relevant evidence in public health decision-making

Hosted by LSE’s Firoz Lalji Institute for Africa in partnership with the London School of Hygiene and Tropical Medicine

Lead Investigator: Cristin Alexis Fergus
LSE Principal Investigtor: Tim Allen

Despite some work on knowledge translation for use in global health policy, there is a surprising lack of information on what is actually useful from a practice standpoint


Project running: March 2019–April 2021

In areas of sub-Saharan Africa, public health practitioners are part of a larger global health system, wherein they implement disease-specific, global health interventions. While these are largely devised and financed by external agents, the information and evidence needed for effective decision-making at the national and sub-national levels have not been extensively studied. 

Through new research and an extensive series of workshops the project will create explicit links between local practitioners and the development evidence, identifying local evidence needs and elucidating the complexity of implementation from the local perspective. Using a complex systems approach, this information will inform the methodological choices and development of evidence fit for purpose.

The LEAD Project focuses on the transmission and control of schistosomiasis and soil-transmitted helminths around the African Great Lakes Region, with fieldwork in epidemiologically-relevant areas of Kenya, Malawi, Tanzania and Uganda.

Background and objectives

Global health has become a multi-billion dollar industry whose product is a set of interventions aimed at decreasing the burden of disease in developing countries. The industry’s emphasis of the MDGs and SDGs on specific disease problems encourages a biomedical, disease-specific approach to tackling ill-health, despite the social-economic-political basis for their persistence.

In recent years, there has been a focus on the utilisation of evidence-based decision-making in global health. While an emphasis on the localisation of this approach is often part of the rhetoric, its realisation has been challenging in practice. The processes of decision-making at different localities are inherently heterogenous and the evidence needs of local practitioners are not well understood.

The LEAD Project addresses these issues with a synergistic approach to evidence development and utilisation between local public health practitioners and researchers at LSE and LSHTM. While there has been some work on knowledge translation for use in global health policy and practice, there is a surprising lack of information on what is actually useful from a practice standpoint, especially from the perspective of local actors. The LEAD Project aims to identify and respond to the needs of local actors by taking advantage of recent technological and computational advances, in particular the processing and identification capabilities of artificial intelligence for application in global health.

The main objectives are:

  • To identify evidence needs of public health practitioners and explore how perceived challenges may impede the use of evidence when implementing global health interventions in their localities.
  • To understand perceptions of transmission and interventions for the control and elimination of schistosomiasis and soil-transmitted helminths.
  • To respond to the needs of practitioners by taking advantage of technological and computational advances, especially artificial intelligence and simulation for application in global health.

Research activities

Workstream 1.
Define local perceptions on disease problem, evidence and decision-making 

Activity 1. Participatory modeling

The LEAD Project facilitated the participatory modeling method Participatory Systems Mapping (hyperlink to CECAN) (PSM) in a series of workshops in Uganda and Malawi. Participants, including health practitioners from the village, district, and national levels in the public and private sectors, developed complex systems maps around schistosomiasis transmission.

Activity 2. Engagement activities

Following the workshops, three engagement activities have been established to foster communication and involvement with the LEAD Project. This includes: co-authored publications and assistance with publication interests of participants; an online community forum for engagement with components of Workstream 2; and a follow-up meeting with participants near the end of the project.

Workstream 2.
Integrate local perceptions and evidentiary needs into the development of evidence

Activity 3. Assembly of available evidence for a public database

The systems maps produced in the workshops went through a minimal cleaning and normalisation process to maintain the integrity of participant input and minimise our biases. These maps were then synthesised to prioritise factors and develop a list of attributes directly and indirectly related to transmission of schistosomiasis. Finally, web scraping and content mining is being used to assemble a database of factors, to be made publicly available at the end of 2020.

Activity 4. Computational modeling

Through the workshops, we have been able to gather information about the evidence gaps for individuals working in a variety of positions in the health sector. Based on feedback and discussions with participants, the LEAD project is developing spatial agent-based models fit for purpose, e.g. to facilitate intervention effectiveness evaluation for resource allocation. This includes a user-friendly interface adapted to the needs of public health practitioners.


Please contact Cristin Fergus at c.fergus@lse.ac.uk for more information.



Shifting Spaces blog

Shifting Spaces from Coronavirus: Unfolding perspectives from the African Great Lakes Region 

Drawing on diverse spatial and temporal moments, this blog series introduces insights from the coronavirus response in Malawi, Uganda, Tanzania and Kenya.

As the coronavirus pandemic marks out an uneven presence across the region, the project will capture local perceptions of the virus and the diverse protections taken against it. This blog series publishes the experiences of health workers and the general population within the shifting spaces of health information, access and provision of health services, disease perceptions and local personal protections.

We foreground experiences in contrasting rural and urban contexts from epidemiologically diverse areas, and offer insights in the context of changing government and civic responses to these extraordinary times. Together, the blogs present a dynamic contribution as to the realities of the virus as they take shape across the African Great Lakes Region.

Learn more about the blog series here.



Tim Allen

Tim Allen is Director of the Firoz Lalji Institute for Africa and Professor of International Development at LSE. He is currently the PI for the five-year ESRC-funded Centre for Public Authority and International Development.

Email: t.allen@lse.ac.uk


Cristin Alexis Fergus

Cristin is Lead Investigator for the LEAD Project and PhD researcher in the LSE Department of International Development, where she examines aspects of evidence for decision-making within global health.

Email: c.fergus@lse.ac.uk


Melissa Parker

Professor Melissa Parker is an adviser on the LEAD Project. She is a medical anthropologist at the Department of Global Health and Development, LSHTM. Melissa has training in Human Sciences and a DPhil from Oxford University.

Email: melissa.parker@lshtm.ac.uk


Georgina Pearson

Georgina is a research fellow on the LEAD Project and is a Clinical Lecturer in Public Health in the Population Health Research Institute at St George’s, University of London. She also holds a PhD from the LSE Department of International Development.

Email: g.f.pearson@lse.ac.uk


Liz Storer

Liz is a researcher on the LEAD Project and a PhD researcher in LSE’s Department of International Development. Her research is based in North-West Uganda and uses ethnographic methods to explore local understandings of health and misfortune.

Email. e.storer@lse.ac.uk


Kate Dawson

Kate is a research assistant on the LEAD Project and holds a PhD in Human Geography and Urban Studies from LSE, where she examined the socio-natural politics of urbanisation in Accra, Ghana.

Email: k.e.dawson@lse.ac.uk


Duncan Njue

Duncan is a development consulting expert with Finnish Consulting Group - Kenya. He holds an MSc in Development Management from the LSE and a BEng in Chemical and Process Engineering from Moi University.



Halfan Hashim Magani

Halfan Hashim Magani is an Assistant Lecturer at the University of Dar es Salaam, where he previously received an MA in Development Management, an MA in History, and previously a BA in Education.



Moses Adriko

Moses Adriko is the Program Officer for NTD Control Program with over 10years experience in NTD Control Program at the Division of Vector Borne & NTD Control of the Uganda Ministry of Health.



Arinaitwe Moses

Arinaitwe Moses is a programme officer within the Uganda ministry of health NTD control program. He works on NTD burden, designing and implementing country specific NTD control interventions and evaluating impact.


Visual Arts for Localised Evidence and Decision-making (VA-LEAD)

This partnership between LSE, SOAS, LSHTM, and PostiveNegatives has received a Bloomsbury SET Arts Humanities and Social Sciences (AHSS) award to commission and produce visual media that follow on the LEAD project’s research findings related to schistosomiasis and soil transmitted helminths in Uganda and Malawi. 

Based at SOAS and led by Principal Investigator Dr Polly Savage, the award supports the production of two visual outputs that communicate the LEAD project’s research in accessible and meaningful ways.  The first is an open call for an artist’s commission to offer innovative perspectives on the prevention of schistosomiasis and helminth infection tailored for audiences in Uganda and Malawi, but accessible globally. The second is the development of graphic narratives for two public health campaigns which will highlight relevant issues, such as water use, and the experiences of health workers who are responsible for the delivery of health interventions within the communities.

This project is supported by the work of Dr Polly Savage (PI, Department of the History of Art and Archaeology, SOAS), Dr Benjamin Dix (Director, PositiveNegatives), Dr Tim Allen (Director, LSE FLCA, LEAD Project), Dr Melissa Parker (LSHTM), Cristin Fergus (Lead Investigator, LSE LEAD Project), Kara Blackmore (LSE).

We will link to the project here soon.



The Firoz Lalji Institute for Africa promotes independent academic research and teaching, open and issue-oriented debate, and evidence-based policy making, in partnership with Africa to bring African voices to the global debate.



The Centre for Public Authority and International Development explores how forms of public authority shape and are shaped by interlocking global challenges with risks and opportunities for development and inclusive growth.



The London School of Hygiene & Tropical Medicine is renowned for its research, postgraduate studies and continuing education in public and global health.




PositiveNegatives produce literary comics, animations and podcasts about contemporary social and humanitarian issues. We combine ethnographic research with illustration, personal testimonies, education and advocacy materials.

Centre for Health, Agriculture, Development Research and  Consulting – CHAD, is a Malawi registered company providing research, internships and consulting services to both local and international organisations.


Bloomsbury Set

The LEAD project is funded by the Bloomsbury SET programme. The Bloomsbury SET (Science, Economics, Technology) programme connects places, people, businesses, ideas and infrastructures to bring forward innovative scientific and technical solutions to help safeguard human health.

Photo credit: UN Women