HP407      Half Unit
Evidence Review and Synthesis for Decision Making

This information is for the 2021/22 session.

Teacher responsible

Dr Huseyin Naci COW 3.01


This course is available on the MSc in Global Health Policy, MSc in Health Data Science, MSc in Health Policy, Planning and Financing, MSc in International Health Policy and MSc in International Health Policy (Health Economics). This course is available as an outside option to students on other programmes where regulations permit.

This course is relevant to all students with an interest in the health and social care interventions. 

Course content

Evidence review and synthesis methods (such as systematic reviews and meta-analyses) are increasingly used to evaluate the effectiveness of healthcare interventions. A broad range of decision making bodies across the health care sector (including health technology assessment bodies, drug and medical device licensing agencies, biopharmaceutical industry, and hospitals) need individuals equipped with the methods of reviewing and synthesising the existing body of evidence by performing systematic reviews and meta-analyses.

This course will be focused on the principles of reviewing and synthesising the existing body of literature. The course will have three components. The first will provide the rationale for adopting a systematic approach for evidence review and synthesis. It will equip students with the methods to undertake risk of bias assessments of randomised controlled trials. The second component will focus on the quantitative synthesis of multiple randomised controlled trials in meta-analysis. The third component will discuss the opportunities and challenges of using evidence for decision-making.

The intended learning outcomes of this course will be the following:

• Describe the rationale for adopting a systematic approach to literature review

• Define the principal threats to validity both in individual randomised trials and collections of randomised trials

• Critically evaluate the quality of randomised controlled trials in oral and written form

• Assess heterogeneity in a collection of studies

• Design and perform a systematic review and meta-analysis evaluating a health care intervention in a group setting

• Describe the opportunities and challenges of using systematic review and meta-analysis findings for decision making


This course will be delivered through a combination of lectures and seminars totalling a minimum 25 hours during Michaelmas Term. Students will work in small groups to complete weekly self-directed learning activities and meet with seminar leads for weekly feedback on their progress. A computer workshop will be held to introduce students to systematic review and meta analysis software.

There will be a departmental reading week in week 6 of term.

Formative coursework

  • Systematic review and meta-analysis protocol (submitted individually) - feedback provided by course instructor

Indicative reading

  • Cochrane Handbook for Systematic Reviews of Inter ventions (version 5.1.0, updated March 2011).
  • Institute of Medicine. Finding what works in health care: standards for systematic reviews. 23 March 2011.
  • Sutton AJ et al. Methods for Meta-analysis in Medical Research. Wiley, Chichester, UK, 2000.
  • Cook DJ. Systematic reviews: synthesis of best evidence for clinical decisions. Annals of internal medicine 1997;126(5):376–80.
  • Higgins, Julian PT, et al. The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials. Bmj 343 (2011): d5928.


Project (100%, 3000 words) in the LT.

Systematic review and meta-analysis report resembling an original article submission to a peer-reviewed journal (100%). Students will develop their meta-analysis project in a group and individually write up as their summative assessment. 

Course selection videos

Some departments have produced short videos to introduce their courses. Please refer to the course selection videos index page for further information.

Student performance results

(2017/18 - 2019/20 combined)

Classification % of students
Distinction 36
Merit 54.7
Pass 9.3
Fail 0

Important information in response to COVID-19

Please note that during 2021/22 academic year some variation to teaching and learning activities may be required to respond to changes in public health advice and/or to account for the differing needs of students in attendance on campus and those who might be studying online. For example, this may involve changes to the mode of teaching delivery and/or the format or weighting of assessments. Changes will only be made if required and students will be notified about any changes to teaching or assessment plans at the earliest opportunity.

Key facts

Department: Health Policy

Total students 2020/21: 55

Average class size 2020/21: 4

Controlled access 2020/21: Yes

Value: Half Unit

Guidelines for interpreting course guide information

Personal development skills

  • Team working
  • Problem solving
  • Communication
  • Application of numeracy skills
  • Specialist skills